For the past five decades, venture capital firms have played a crucial role in shaping the U.S. economy into its current capitalist powerhouse. Many of the world’s largest companies by market capitalization, including Apple, NVIDIA, Microsoft, Amazon, and Meta, attribute part of their initial success to funding from VC firms when they were just beginning, making these VC firms some of the most influential businesses globally.

To highlight the entities that are molding the business landscape, TIME and Statista evaluated 350 VC firms leading the way in accelerating innovation, supporting emerging startups, and driving the next wave of economic expansion. These firms primarily focus on providing direct venture capital funding to companies and startups across various stages and sectors. Their ranking was determined by their fundraising capabilities over the last five years, their investment capacity, and the volume and efficiency of their exits through IPOs and acquisitions.

These firms provide private equity to young, innovative, and frequently high-risk companies that possess significant growth potential. For instance, Accel (ranked #1 on the list) has funded , , Slack, and Spotify; General Catalyst (ranked #2) has invested in , , and ; and Andreessen Horowitz (ranked #3) has supported , , , and .

“We have been operating since 1983, investing in technology startups,” stated Sameer Gandhi, a partner at Accel. “Our goal is to be the first and primary institutional investor. We aim to be involved very early on. We begin with compelling ideas and exceptional individuals, and we build alongside them from there.” Accel has demonstrated strong confidence in AI-native companies, including and .

“Venture capital propelled the internet. Venture capital propelled mobile. And venture capital is currently propelling AI,” remarked , a professor at the University of Chicago Booth School of Business. Companies often choose VCs over more traditional financing methods like banks because VCs are typically more willing to embrace higher risks. Additionally, they offer greater mentorship, assist startups in forming management teams, and connect them with suppliers and customers.

For Accel, its competitive advantage stems from its deep involvement in supporting companies during their nascent stages, offering not just financial backing but also industry knowledge and perspectives. Slack and CrowdStrike, for example, were early investments that Accel supported throughout their development. Notably, Accel was among the initial investors in Scale AI and spearheaded a funding round for the company in 2024. The firm is now reportedly expected to receive a payout of $2.5 billion from Meta’s acquisition of Scale, according to .

While tech startups often draw more attention in portfolios, VC firms invest in groundbreaking ideas across diverse industries, supporting businesses ranging from to mRNA vaccine developer to . Kaplan stated, “The small number of [U.S. businesses] that receive venture funding—those are disproportionately the major successes. [VC firms] are very adept at selecting the ones that are poised to flourish. And generally, they are also highly skilled at establishing incentives and governance structures that lead to success.” He acknowledged that this process is not easy. “If you examine the deals venture capitalists invest in, more than half result in financial losses,” he observed. “It is the few significant successes that .”

Most of the VC firms on this list are located on the coasts—over half are headquartered in California, home to Silicon Valley, followed by New York, Massachusetts, and emerging startup centers . Drive (ranked #93) is an anomaly, based in the Midwest, a location its CEO Chris Olsen views as an asset. Olsen, who grew up in Ohio, left Sequoia Capital in 2012 to co-found Drive in Columbus. “By the time I departed,” he noted, “the technological advancements in cloud computing suddenly meant that being in Silicon Valley was no longer a necessity.” Currently, Drive is a $2 billion firm with companies like Duolingo in its portfolio and a pipeline of over a dozen near-IPO companies generating more than $100 million in revenue.

“There is $18 trillion in GDP between the coasts,” Olsen remarked, adding that founders in America’s heartland benefit from hands-on experience and specialized knowledge in their respective industries, whether that’s welding or healthcare. This makes them well-suited to understand how new technologies such as mobile, cloud, or AI will operate in practical applications. “We are bringing venture capital directly to the founders. We encourage them to remain close to their research, their families, their networks, and their customers.”

However, while the venture capital firm is fundamentally an American business model, some, like 500 Global (ranked #41), embrace a more international perspective. With a team spanning 20 different countries and a portfolio that encompasses over 80 countries, 500 Global takes pride in supporting startups across numerous markets worldwide. “If you look at our portfolio, our team, particularly among leadership and investment partners, it appears quite different from many venture firms. It is remarkably diverse,” stated Christine Tsai, CEO and founding partner of 500 Global. Her firm is challenging a noticeable and disparity, both among founders and investors, even though research indicates that having more female partners and often leads to .

“The fact that our team is so diverse, and we are committed to investing in exceptional founders everywhere, across industries, sectors, or customer segments that many might overlook, has led to our current achievements,” Tsai commented. Approximately 30% of 500 Global’s portfolio companies include at least one female founder, and 53% of their managing partners are women. Excellent examples of the firm’s investment preferences include Australian unicorn (led by CEO Melanie Perkins), (which operates in Japan and Silicon Valley), and Play AI (a voice AI startup co-founded by international individuals).

The complete roster of top VC firms is provided below:

Applications constitute a key part of the project’s selection process. For next year’s list, the application period is anticipated to open in spring 2026. To be notified upon its commencement, you may register .